Without recombination what are the probability that my parents could conceive another exchangeable me?



Answers:    Each parent has 46 chromosomes contained by 23 pairs: two of #1, two of #2, two of #3, and so on. Your mother gives you one #1, one #2, etc, where on earth each egg get a different random combination - liberal of like flipping a coin 23 times, and keeping track of the exact sequence of head and tails, choosing one or the other of respectively chromosome. There are a bit over 8 million combinations of chromosomes your mother could have given your.

Same next to your father, except for the X/Y chromosome. You (a girl) got the X and not the Y, so singular the other 22 chromosomes are in the coin-tossing team game. That's about 4 million. Between your mother and father, that's 45 coin flips, or give or take a few 32 trillion possible combinations - about five thousand times the population of the planet.

Let's assume nearby are no lethal recessives to verbs about, or immunological incompatibility beside the mother (like Rh disease, but there are others), and you already disqualified recombination. If your parents kept have kids until they had another one only like you, genetically, that would be give or take a few half of 32 trillion (in some statistical sense), or 16 trillion - more than 2000 times the Earth's population. A slightly different quiz would ask: when would they have two kids beside identical chromosomes, not necessarily yours, but that's a "birthday paradox" press. They'd have to enjoy 5-6 million kids to get an even break of some two among all those have the same chromosomes.

Long formerly that, your mother would have have your father sterilized at gunpoint.

All that ignores gene silencing. Especially on the X chromosomes, you bring back a double dose of each gene, but not necessarily indistinguishable allele. (An allele is a different version of a gene, similar to the A blood type vs. B blood type.) It's bad to enjoy genes too active, so gene silencing attaches a attraction to the gene on one chromosome or the other, telling it to hush up. If the two copies of that gene are different alleles, afterwards silencing one instead of the other results in a different phenotype. I don't know how heaps genes are subject to gene silencing, but there are a few. That's why very same (monozygotic) twins aren't 100% identical, and why girl monozygotics are more different from respectively other than boys - they enjoy more X genes to choose from when the gene silencing happens. I don't know the numbers, but gene silencing mode that there are lots more than 32 trillion possibilities - conceivably thousands or millions times as many different possibilities.

Even if they get lucky on the 1:32,000,000,000,000 chance, and even if gene silencing somehow picked alike set of genes to silence, where the alleles are different, environment and experience would label you into different people. Two of my cousins are monozygotic twins, but you'd never know it to look at them. Life have treated them very differently, and it shows.

Rest smooth. You're unique. You are the individual you there is, and other will be.
cloning. I don't know because I'm too lazy to work it out, but I'm guessing it would be one surrounded by several billion.

That's assuming that there's another egg inside your mother that was indistinguishable as yours...now I deem about it I don't know if this happen or not. So it might not be possible. But theoretically it is, close to I said really tiny chance though.
It's impossible to hold someone identical to you, unless they are your very twin.

Siblings have different DNA.

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