Has anyone ever have any success near treating interstitial cystitis?
Answers:
My mother had interstitial cystitis and be successfully treated with DMSO, it be quite a while ago immediately (more than ten years). I just remember her have it was horrible, bleeding, incontinence (urinary), etc. I also remember that after an initial hospital stay (because they didn't know what it be at the time) she would go contained by they would fill her bladder next to DMSO, leave it contained by for awhile and then drain it and she would run home. I don't know if the doctors shied away from using other medications first because of her complex medical problems. Hope the following help... I pulled it from Wiki...
From Wiki: http://en.wikipedia.org/wiki/interstitia...
Treatment
[edit] Diet
The foundation of therapy is a modification of diet to minister to patients avoid those foods which can will further irritate the damaged bladder wall. Common offender include coffees, teas, herbal teas, green teas, all sodas (particularly diet), concentrated fruit juice, multivitamins, monosodium glutamate, chocolate, and potassium-rich foods such as bananas. Most IC support groups and many urology clinics hold diet lists available.
The problem next to diet triggers is that they vary from personality to person: the best opening for a person to discover his or her own triggers is to use an expulsion diet. This is where someone cuts out adjectives foods except the basics (e.g. potatoes, bread, rice, water) and later introduces new foods one at a time. Trying to discover which foods are one's own triggers in need the use of an elimination diet is resembling trying to do a scientific experiment whilst altering 10 variables adjectives at once.[10][11]
[edit] Bladder coatings
As recently as a decade ago, treatments available be limited to the use of astringent instillations, such as clorpactin or silver nitrate, designed to slay infection and/or strip off the bladder facing. In 2005, our understanding of IC have improved dramatically and these therapy are now no longer done. Rather, IC psychiatric help is typically multi-modal, including the use of a bladder coating, an antihistamine to help control flagstaff cell activity and a low dose antidepressant to confrontation neuroinflammation.[12]
The two US FDA approved therapies for IC enjoy had recent setbacks surrounded by various research studies. Oral Elmiron (aka pentosan polysulfate) is believed to provide a protective coating in the bladder, however information released in unpunctually 2005 by Alza Pharmaceuticals suggests that 84% of Elmiron is eliminated, intact, in feces. Another 6% is excreted via urine.[13] In adjunct, the NIH funded ICCTG study of pentosan revealed results only slightly better than placebo.[14] The latter study be criticized, however, for targeting solely the most severe IC patients who were also the tiniest likely to respond (i.e. the NIDDK diagnostic criteria).
DMSO, a wood pulp extract, is the merely approved bladder instillation for IC yet it is much smaller quantity frequently used in urology clinics. Research studies presented at recent conferences of the American Urological Association by C. Subah Packer own demonstrated that the FDA approved dosage of a 50% solution of DMSO had the potential of creating irreversible muscle contraction. However, a less significant solution of 25% was found to be reversible. Long permanent status use is questionable, at best, particularly given the reality that the method of action of DMSO is not fully inherent.[15]
More recently, the use of a "rescue instillation" composed of elmiron or heparin, cystistat, lidocaine and sodium bicarbonate, have generated considerable excitement contained by the IC community because it is the first therapeutic intervention that can be used to diminish a flare of symptoms. Published studies report a 90% effectiveness within reducing symptoms.[16]
Other bladder coating therapies include Cystistat(TM) (sodium hyaluronate) and Uracyst(TM) (chondroitin). They are believed to replace the not up to scratch GAG layer on the bladder wall. Like most other intravesical bladder treatments, this treatment may require the forgiving to lie for 20 - 40 minutes, turning over every ten minutes, to allow the chemical to 'soak in' and pass a good coating, in the past it is passed out with the urine.
[edit] Pelvic floor treatments
Pelvic floor dysfunction may also be a contributing factor thus most primary IC clinics now evaluate the pelvic floor and/or refer patients directly to a physical psychoanalyst for a prompt treatment of pelvic floor muscle tension or impediment. Pain in the bladder and/or pelvis can trigger long term, chronic pelvic floor rigidity which is often described by women as a burning sensation, expressly in the vagina. Men near pelvic floor tension experience referred distress, particularly at the tip of their penis. In 9 out 10 IC patients struggling beside painful sexual relations, muscle rigidity is the primary cause of that strain and discomfort. Tender trigger points, small tight bundles of muscle, may also be found in the pelvic floor.[17]
Pelvic floor dysfunction is a fairly tentative area of specialty for physical therapist world wide. The desire of therapy is to relax and extend the pelvic floor muscles, rather than to tighten and/or strengthen them as is the dream of therapy for patients next to incontinence. Thus, traditional exercises such as Kegels, can be helpful as they strengthen the muscles, however they can provoke headache and additional muscle rigidity. A specially trained physical therapist can provide direct, hand on, evaluation of the muscles, both externally and internally. While weekly therapy is absolutely valuable, most providers also suggest an aggressive self-care regimen at home to back combat muscle tension, such as each day muscle relaxation audiotapes, stress reduction and anxiety headship on a daily starting place. Anxiety is often found within patients with raw conditions and can subconsciously trigger muscle tension.
[edit] Pain control
Pain control is usually requisite in the IC treatment plan. The strain of IC has be rated equivalent to cancer distress and should not be ignored to avoid main sensitization. The use of a variety of traditional twinge medications, including opiates, is repeatedly necessary to treat the varying degree of pain. Complementary therapy such as acupuncture, massage, and biofeedback are also beneficial to some patients. Even children beside IC should be appropriately addressed concerning pelvic pain, and receive basic treatment to manage it.[18]
Electronic pain-killing option include TENS (a machine connected to sticky pad which one places on their body at certain pressure points; the TENS apparatus sends electrical impulses to the skin, using the human body as an 'dirt'). PTNS stimulators have also be used, with varying degree of success. This is similar to a TENS treatment, except a hypodermic is used rather than sticky pad.
[edit] Other treatments
Bladder distentions (a procedure which stretches the bladder capacity, done lower than general anaesthetic) own shown some success contained by reducing urinary frequency and giving pain nouns to patients. However, many experts still cannot realize precisely how this can cause cramp relief. Unfortunately, the nouns achieved by bladder distentions is singular temporary (weeks or months) and consequently, it is not really viable as a long-term treatment for Interstitial Cystitis: it is roughly only used within extreme cases.
Surgical interventions are rarely used for IC. Neurostimulation technique are not FDA approved for IC.
[edit] Links to other conditions
It is important to record that some people next to IC suffer from Anxiety disorder, and other conditions that may have equal etiology as IC. These include: irritable bowel syndrome (IBS), Fibromyalgia, Endometriosis, Vulvodynia, and chemical sensitivities. Men with IC are frequently diagnosed as have prostatitis, and there is an extensive overlap of symptoms and treatment between the two conditions, major some researchers to posit that the conditions share the same etiology and pathology.
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